High-scatter T cells: a reliable biomarker for malignant T cells in cutaneous T-cell lymphoma

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High-scatter T cells: a reliable biomarker for malignant T cells in cutaneous T-cell lymphoma.

In early-stage cutaneous T-cell lymphoma (CTCL), malignant T cells are confined to skin and are difficult to isolate and discriminate from benign reactive cells. We found that T cells from CTCL skin lesions contained a population of large, high-scatter, activated skin homing T cells not observed in other inflammatory skin diseases. High-scatter T (T(HS)) cells were CD4(+) in CD4(+) mycosis fung...

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LYMPHOID NEOPLASIA High-scatter T cells: a reliable biomarker for malignant T cells in cutaneous T-cell lymphoma

In early-stage cutaneous T-cell lymphoma (CTCL), malignant T cells are confined to skin and are difficult to isolate and discriminate from benign reactive cells. We found that T cells from CTCL skin lesions contained a population of large, highscatter, activated skin homing T cells not observed in other inflammatory skin diseases. High-scatter T (THS) cells were CD4 in CD4 mycosis fungoides (MF...

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ژورنال

عنوان ژورنال: Blood

سال: 2011

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood-2010-05-287664